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The use of recombinant antibodies in proteomics

✍ Scribed by Lucy J Holt; Carolyn Enever; Ruud MT de Wildt; Ian M Tomlinson

Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
217 KB
Volume
11
Category
Article
ISSN
0958-1669

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✦ Synopsis

Recombinant antibodies are becoming increasingly important in the field of proteomics. Recent advances include the development of large phage-antibody libraries that contain high-affinity binders to almost any target protein, and new methods for high-throughput selection of antibody-antigen interactions. Coupled with a range of new screening technologies that use high-density antibody arrays to identify differentially expressed proteins, these antibody libraries can be applied to whole proteome analysis.

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