𝔖 Bobbio Scriptorium
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The use of radioisotopes in the physical sciences and industry


Publisher
Elsevier Science
Year
1960
Weight
50 KB
Volume
8
Category
Article
ISSN
0020-708X

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A rapid and sensitive HPLC-based method for quantitating isoaspartate levels in peptides and proteins is described. The analyte is incubated for 40 min with S-adenosyl-L-methionine and the commercially available enzyme protein L-isoaspartyl methyltransferase. Methylation of isoaspartyl sites results