Fluoroacetate and its toxic metabolite fluorocitrate cause inhibition of aconitase. In brain tissue, both substances are preferentially taken up by glial cells and leads to inhibition of the glial TCA cycle. It is important to realise, however, that the glia-specificity of these compounds depends bo
The use of radio-isotopes in the study of protein, nucleic acid and glycogen metabolism in the brain and the peripheral nerves
✍ Scribed by A.V. Palladin
- Publisher
- Elsevier Science
- Year
- 1957
- Weight
- 100 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0020-708X
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📜 SIMILAR VOLUMES
## Abstract | I. | Introduction | 306 | | II. | Supramolecular Structure Characterization | 308 | | | A. A Protein Is Used as a “Hook” | 309 | | | 1. Immuno‐Precipitation | 309 | | | 2. Tagging with a Poly‐Histidine Sequence | 310 | | | 3. Direct Analysis of Large Protein Complexes | 3
## Abstract Early biochemical analyses of metabolic pathways assumed that the free diffusion of substrates and enzymes in an evenly mixed cellular space provided the interactions that enabled reactions to proceed. Metabolic complexes have since been shown to assemble and disassemble in response to