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The use of physiologically-based pharmacokinetic/ pharmacodynamic dosimetry models for chemical mixtures

✍ Scribed by Raymond S.H. Yang; Hisham A. El-Masri; Rüssel S. Thomas; Alexander A. Constan

Book ID
118411983
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
827 KB
Volume
82-83
Category
Article
ISSN
0378-4274

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## Abstract Physiologically based pharmacokinetic (PBPK) models are sophisticated dosimetry models that offer great flexibility in modeling exposure scenarios for which there are limited data. This is particularly of relevance to assessing human exposure to environmental toxicants, which often requ