The t-butoxy group, a novel hydroxyl-pro
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H. C. Beyerman; J. S. Bontekoe
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Article
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2010
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Elsevier Science
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English
β 378 KB
## Abstract We have found a novel way of protecting the hydroxyl function in hydroxyβLβamino acids, making use of the tβbutoxy group, which is readily split by acids, but not by bases. This group is introduced by acidβcatalysed addition of isobutene to Nβacylated hydroxyβLβamino acids. The blockin