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The Use of Orthologous Sequences to Predict the Impact of Amino Acid Substitutions on Protein Function

โœ Scribed by Marini, Nicholas J.; Thomas, Paul D.; Rine, Jasper; Zhang, Jianzhi

Book ID
120201749
Publisher
Public Library of Science
Year
2010
Tongue
English
Weight
658 KB
Volume
6
Category
Article
ISSN
1553-7390

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The multidimensional statistical technique of discriminant analysis is used to allocate amino acid sequences to one of four secondary structural classes: high a content, high / 3 content, mixed a and @, low content of ordered structure. Discrimination is based on four attributes: estimates of percen