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The Use of Minipigs in Dermal Toxicity Testing

✍ Scribed by Vogel, B. ;Singer, T.


Book ID
111262472
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
51 KB
Volume
80
Category
Article
ISSN
0901-9928

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The dermal absorption of niclosamide, a drug shown to prevent Schistosomiasis by blocking the dermal penetration of cercariae, has been examined in Sinclair minipigs and rats. Radioactivity in the urine and feces collected daily for 7 days after application of ''C-niclosamide accounted for less than