Randomized comparison of moderate-dose m
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Lange, Beverly J.; Blatt, Julie; Sather, Harland N.; Meadows, Anna T.
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Article
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1996
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John Wiley and Sons
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English
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Methotrexate (MTX) infusions of 500-1,000 mg/m2 over 24 hours may improve survival and prevent relapse in children with acute lymphoblastic leukemia (ALL). Childrens Cancer Group (CCG) Study 139 compared weekly oral methotrexate 20 mg/m2/ week (oral MTX) to MTX 500 mg/m2 infused over 24 hours (IV MT