The use of in vivo brain dialysis of dopamine, acetylcholine, aminoacids and lactic acid in studies on the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

Behavioral motor recovery in the 1-methy

Behavioral motor recovery in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned squirrel monkey (Saimiri sciureus): Changes in striatal dopamine and expression of tyrosine hydroxylase and dopamine transporter proteins

✍ Giselle M. Petzinger; Beth Fisher; Elizabeth Hogg; Avery Abernathy; Pablo Areval 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 931 KB

## Abstract The neurotoxicant 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) provides an excellent opportunity to study repair and response to injury in the basal ganglia. Administration to mammals leads to the destruction of nigrostriatal dopaminergic neurons and depletion of striatal dopamin