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The use of healthy volunteers instead of patients to inform drug dosing studies: a [11C]raclopride PET study

โœ Scribed by Euitae Kim; Oliver D. Howes; Bo-Hyung Kim; Kyung-Sang Yu; Jae Min Jeong; Jae Sung Lee; Su Jin Kim; In-Jin Jang; Jung Shin Park; Yong Gil Kim; Sang-Goo Shin; Federico E. Turkheimer; Shitij Kapur; Jun Soo Kwon


Publisher
Springer
Year
2011
Tongue
English
Weight
260 KB
Volume
217
Category
Article
ISSN
0033-3158

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A PET Study on the Acute Effect of Ethan
โœ IIRIS SALONEN; JARMO HIETALA; ARTO LAIHINEN; PERTTI LEHIKOINEN; LASSE LEINO; KJE ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 146 KB ๐Ÿ‘ 2 views

The eect of acute oral ethanol intake (1 . 0 g/kg) on cerebral D2-receptors ([ 11 C]raclopride binding) was studied in seven healthy volunteers, using water and alcohol in two separate 59-min PET sessions. In the alcohol experiments, the blood ethanol concentration at the beginning of the imaging wa