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The use of granulocyte colony-stimulating factor to increase the intensity of treatment with doxorubicin in patients with advanced breast and ovarian cancer

✍ Scribed by Bronchud, MH; Howell, A; Crowther, D; Hopwood, P; Souza, L; Dexter, TM


Book ID
109836196
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
962 KB
Volume
60
Category
Article
ISSN
0007-0920

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## Background: Topotecan is a new antineoplastic agent with a broad spectrum of activity. the purpose of this phase i trial was to define the maximum tolerated dose of topotecan when added to the widely used combination of paclitaxel and carboplatin. ## Methods: Patients with advanced cancer that