## Abstract Neighboring common polymorphisms are often correlated (in linkage disequilibrium (LD)) as a result of shared ancestry. An association between a polymorphism and a disease trait may therefore be the indirect result of a correlated functional variant, and identifying the true causal varia
β¦ LIBER β¦
The use of genetic correlations to evaluate associations between SNP markers and quantitative traits
β Scribed by J. T. Brawner, S. K. Dillon, D. J. Lee, A. R. Meder, M. J. Dieters, Simon G. Southerton
- Book ID
- 118812819
- Publisher
- Springer-Verlag
- Year
- 2012
- Tongue
- English
- Weight
- 449 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1614-2942
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## Abstract With the increasing availability of genetic data, several SNPs in a candidate gene can be combined into haplotypes to test for association with a quantitative trait. When the number of SNPs increases, the number of haplotypes can become very large and there is a need to group them toget
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