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The use of fluorescein-dipalmitoylphosphatidylethanolamine for measuring pH-changes in the internal compartment of phospholipid vesicles

โœ Scribed by Marcus Thelen; Goffredo Petrone; Paul S. O'Shea; Angelo Azzi


Book ID
115718545
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
599 KB
Volume
766
Category
Article
ISSN
0005-2728

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It is demonstrated that irradiation of the anticancer drug flutamide (FM) in the presence of unilamellar phospholipid bilayer vesicles, chosen as a model for cell membranes, leads to an efficient photobinding process. This pathway is triggered by an unexpected hydrogen-abstraction reaction of the ex