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The use of endothelial cell plasma membrane vesicles for the study of fibrinolytic enzyme kinetics at the endothelial cell surface

✍ Scribed by H. Zoellner; R. Beckmann; B.R. Binder

Book ID
119154471
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
140 KB
Volume
8
Category
Article
ISSN
0268-9499

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## Abstract Insulin degrading enzyme (IDE) is expressed in the brain and may play an important role there in the degradation of the amyloid beta peptide (AΞ²). Our results show that cultured human cerebrovascular endothelial cells (HCECs), a primary component of the blood–brain barrier, express IDE