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The use of electrophysiological markers in linkage analysis in schizophrenic and bipolar pedigrees

โœ Scribed by Sharp, C.W.; Blackwood, D.H.R.; Muir, W.J.; Walker, M.; Clair, D.M.St.

Book ID
122895225
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
230 KB
Volume
6
Category
Article
ISSN
0920-9964

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We have used genetic linkage analysis in an effort to identify a gene responsible for bipolar affective disorder (BAD) in an Old Order Amish pedigree. The initial study of this pedigree showed strong evidence for linkage of the chromosome 11p15 markers HRAS1 and the insulin gene (INS) to BAD, wherea