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The use of dogs as second species in regulatory testing of pesticides

✍ Scribed by Horst Spielmann; Ulrich Gerbracht

Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
396 KB
Volume
75
Category
Article
ISSN
0340-5761

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Significance of the dog as β€˜second anima
Significance of the dog as β€˜second animal species’ in toxicity testing for establishing the lowest β€˜no-toxic-effect level’
✍ L. M. Appelman; V. J. Feron πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 618 KB

The toxicity data of 66 compounds adequately tested in the rat (as 'prime animal species') and in the dog (as 'second animal species') were studied to find out for how many of these compounds the study in dogs led to a lower 'no-toxic-effect level' (NTEL) than that found in the rat. From a quantitat