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The use of components of plant origin in the development of production technology for live cold-adapted cultural influenza vaccine

✍ Scribed by N. A. Mazurkova; T. D. Kolokol’tsova; E. A. Nechaeva; L. N. Shishkina; A. N. Sergeev

Publisher
Springer US
Year
2008
Tongue
English
Weight
205 KB
Volume
146
Category
Article
ISSN
0007-4888

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A procedure to attenuate live influenza virus of type A and type B was developed using adaptation of the virus to grow at 25 degrees C (cold adaptation; ca). Through a series of stepwise passages, two stable mutants were obtained and designated as 'Master' strains, one for type A influenza virus (A/