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The use of cis-parinaric acid to measure lipid peroxidation in cardiomyocytes during ischemia and reperfusion

✍ Scribed by Rineke H.G. Steenbergen; Gregor P.C. Drummen; Jos A.F. Op den Kamp; Jan A. Post


Book ID
117048789
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
964 KB
Volume
1330
Category
Article
ISSN
0005-2736

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cis-Parinaric acid (PnA), cis-trans-trans-cis-9, 11, 13, 15-octadecatetraenoic acid, is fluorescent (epsilon = 74,000 at 324 nm) when partitioned into a lipid environment and the fluorescence is destroyed upon reaction with free radicals. It has been used to monitor semiquantitatively free-radical-i