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The use of capillary electrophoresis in a micropreparative mode: Methods and applications

✍ Scribed by Michael Albin; Shiaw-Min Chen; Andrea Louie; Claire Pairaud; Joel Colburn; John Wiktorowicz

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
551 KB
Volume
206
Category
Article
ISSN
0003-2697

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✦ Synopsis

The ability to collect sufficient quantities of analytes from capillary electrophoresis for subsequent analyses is demonstrated. Fractions collected have been analyzed using the following techniques: capillary electrophoresis, mass spectrometry, and protein sequencing. Fractions can be collected directly into small volumes of buffer or directly onto membrane surfaces. Relevant parameters such as capillary diameter, mass loading, and separation parameters are addressed.

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## Application of a capillary electrophoresis method for simultaneous determination of preservatives in pharmaceutical formulations Preservatives are used to protect pharmaceutical formulations from microbial attack during the period of administration to the patient. Because of their biological act