## Abstract ## BACKGROUND Advanced tumors often metastasize to bone, resulting in a variety of skeletal complications. Bisphosphonates are potent inhibitors of osteoclast‐mediated bone resorption that reduce the incidence and delay the onset of skeletal complications and reduce the need for radiat
✦ LIBER ✦
The Use of Bone Markers in a 6-Week Study to Assess the Efficacy of Oral Clodronate in Patients with Metastatic Bone Disease
✍ Scribed by J. E. Brown; E. V. McCloskey; J. A. Dewar; J. J. Body; D. A. Cameron; A. N. Harnett; M. Ruutu; O. P. Purohit; R. Tähtelä; R. E. Coleman
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 308 KB
- Volume
- 81
- Category
- Article
- ISSN
- 1432-0827
No coin nor oath required. For personal study only.
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## Background: Although clinical investigations of bone turnover markers in prostate cancer patients have been conducted, the relationships of pretreatment levels of the markers to the prognosis of patients with bone metastasis has not been fully examined. ## Methods: The serum levels of carboxy-