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The use of aqueous dimethylamine as reagent for the regiospecific C4-epimerization of cis-3-substituted 4-formyl-2-azetidinones

✍ Scribed by Benito Alcaide; Moustafa F. Aly; Alberto Rodríguez-Vicente


Book ID
104259612
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
148 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


A simple and efficient method for the synthesis of trans-3-substituted 4-formyl-2-azetidinones 2 is described based on the regiospecific C4-epimerization of the cisisomers 1 using aqueous dimethylamine as reagent in heterogeneous medium.


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