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The use of animal pharmacokinetic data to evaluate human dosing

โœ Scribed by M. L. LEE


Book ID
108775298
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
33 KB
Volume
16
Category
Article
ISSN
1351-8216

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โœ Toshihiro Wajima; Kazuya Fukumura; Yoshitaka Yano; Takayoshi Oguma ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 145 KB

The aim of the study reported here was to develop a regression equation for predicting oral clearance of various kinds of drugs in humans using experimental data from rats and dogs and molecular structural parameters. The data concerning the oral clearance of 87 drugs from rats, dogs, and humans wer