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The use of adalimumab in the management of refractory Crohn’s disease

✍ Scribed by G.-T. HO; L. SMITH; S. AITKEN; H. M. LEE; T. TING; J. FENNELL; C. W. LEES; K. R. PALMER; I. D. PENMAN; A. G. SHAND; I. D. ARNOTT; J. SATSANGI

Book ID
108605212
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
100 KB
Volume
27
Category
Article
ISSN
0269-2813

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## Background: In the two benchmark controlled trials in Crohn's disease (CD) supporting its use, methotrexate (MTX) was used as the immunosuppressant of choice in immunomodulatory-naive patients. However, in daily clinical practice MTX is used generally after thiopurine analogs have failed. ## Me