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The unresolved origin of uniparental diploid cell lines

✍ Scribed by Carme Morales; Anna Soler; Irene Mademont-Soler; Aurora Sánchez

Book ID
116476501
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
41 KB
Volume
93
Category
Article
ISSN
1556-5653

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## Abstract We present molecular data to demonstrate that the isochromosome 12p, specific for human germ cell tumors (GCTs), is of uniparental origin. Eight GCT‐derived cell lines, containing one or more copies of i(12p) and/or other 12p anomalies, were analyzed with different 12p‐derived polymorph