THE [UNK]SYNTHESIS OF [UNK]CONDENSED [UNK]RING COMPOUNDS. XIV. 2-METHOXY-5-METHYL-2,7-NAPHTHITADIENE-1,4-DIONE 1
โ Scribed by ORCHIN, MILTON; BUTZ, LEWIS W.
- Book ID
- 120280021
- Publisher
- American Chemical Society
- Year
- 1943
- Tongue
- English
- Weight
- 426 KB
- Volume
- 08
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
An optimized total synthesis of the 2-amino-6-chloro-4-cyclopropyl-7-fluoro-5-methoxy-pyrido[1,2-c]pyrimidine-1,3-dione core structure of a new fluoroquinolone-like class of antibacterial agents is described. This synthesis is highlighted by a nearly quantitative ring-closing reaction to form the py
## Abstract Pentadeuteriophenyl clobazam 5 was synthesized in essentially quantitative isotopic purity, and characterized by ^1^HโNMR and mass spectroscopy. The title compound was found to be โฅ98% pure by HPLC, and its retention time (t~R~ 6.17 min) was less than that of an authentic clobazam stand