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The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase

✍ Scribed by Sam Kaitaniemi; Heli Elovaara; Kirsi Grön; Heidi Kidron; Janne Liukkonen; Tiina Salminen; Marko Salmi; Sirpa Jalkanen; Kati Elima


Publisher
Springer
Year
2009
Tongue
English
Weight
609 KB
Volume
66
Category
Article
ISSN
1420-682X

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Methylglyoxal, a toxic aldehyde, has been reported to be increased in diabetes and has been claimed to be related to diabetic complications. Aminoacetone, an intermediate in the metabolism of threonine and glycine, has been proposed to be an endogenous substrate for semicarbazide-sensitive amine oxi