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The unique activity of bone morphogenetic proteins in bone: a critical role of the Smad signaling pathway

โœ Scribed by Katagiri, Takenobu; Tsukamoto, Sho

Book ID
121855473
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2013
Tongue
English
Weight
979 KB
Volume
394
Category
Article
ISSN
1431-6730

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## Abstract Bone morphogenetic protein (BMP)โ€2 plays an important role in bone growth and regeneration; however, BMPโ€2 is easily lost by diffusion through body fluid and has some inhibitory pathways. To address this problem, we previously immobilized recombinant human BMPโ€2 (rhBMPโ€2) on succinylate