The underlying mechanisms of verbal fluency deficit in frontotemporal dementia and semantic dementia
✍ Scribed by Mickaël Laisney; Vanessa Matuszewski; Florence Mézenge; Serge Belliard; Vincent de la Sayette; Francis Eustache; Béatrice Desgranges
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 310 KB
- Volume
- 256
- Category
- Article
- ISSN
- 0340-5354
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Tau is a multifunctional protein that was originally identified as a microtubule-associated protein. In patients diagnosed with frontotemporal dementia and parkinsonism linked to chromosome 17, mutations in the gene encoding tau (MAPT) have been identified that disrupt the normal binding of tau to t
## Abstract ## Introduction: Inclusion‐body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD) is an autosomal dominant disorder due to mutations in the valosin‐containing protein (VCP) gene. Patients with this disorder may have neuropathic or myopathic features. ## Methods