The ultrasound promoted Knoevenagel condensation of aromatic aldehydes

✍ Scribed by James McNulty; Jennifer A. Steere; Sonja Wolf

• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 213 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)01789-4

✦ Synopsis

Application of ultrasound has been found to greatly assist the Knoevenagel aldol condensation reaction of activated methylenes with aromatic aldehydes under mild conditions. The outcome of the ultrasound-promoted reaction depends upon the electronic nature of the aromatic aldehyde, the solvent employed and the addition of acids, bases or ammonium salts.