Chondroitin sulfate (CS) proteoglycans have been implicated as molecules that are involved in axon guidance in the developing neural pathways. The spatiotemporal expression of CS was investigated in the developing retinofugal pathway in mouse embryos by using the CS-56 antibody. Immunoreactive CS wa
The ubiquitous occurrence of chondroitin sulfates in chick embryos
โ Scribed by Abrahamsohn, Paulo A. ;Lash, James W. ;Kosher, Robert A. ;Minor, Ronald R.
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 702 KB
- Volume
- 194
- Category
- Article
- ISSN
- 0022-104X
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โฆ Synopsis
Abstract
The synthesis of sulfated glycosaminoglycans has been studied in a wide variety of embryonic chick tissues. All tissues studied have the capability to manufacture, but not necessarily accumulate, the chondroitin sulfates as well as other glycosaminoglycans. The relative distribution of glycosaminoglycans differs between tissues and changes with age.
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Avian gastrulation is dependent on the ingression of outer layer cells into the interior of the embryo by means of a transient structure referred to as the primitive streak. As the growing streak progresses through the central area pellucida of the blastoderm, selective de-epithelialization of epibl