The ubiquitin–proteasome pathway and viral infections in articular cartilage of patients with osteoarthritis
✍ Scribed by Raquel Rollín; Roberto Álvarez-Lafuente; Fernando Marco; Luis López-Durán; José Antonio Hoyas; Juan Ángel Jover; Benjamín Fernández-Gutiérrez
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 229 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0172-8172
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## Abstract ## Objective To investigate whether heterozygosity for a loss‐of‐function mutation in the gene encoding the α1 chain of type XI collagen (__Col11a1__) in mice (chondrodysplasia, __cho__) causes osteoarthritis (OA), and to understand the biochemical and biomechanical effects of this mut
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