The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

✍ Scribed by Tomlinson, Ian; Lamlum, Hanan; Ilyas, Mohammad; Rowan, Andrew; Clark, Susan; Johnson, Victoria; Bell, Jennie; Frayling, Ian; Efstathiou, Jason; Pack, Kevin; Payne, Stewart; Roylance, Rebecca; Gorman, Patricia; Sheer, Denise; Neale, Kay; Phillips, Robin; Talbot, Ian; Bodmer, Walter

• Book ID: 109493010
• Publisher: Nature Publishing Group
• Year: 1999
• Tongue: English
• Weight: 268 KB
• Volume: 5
• Category: Article
• ISSN: 1078-8956
• DOI: 10.1038/12511