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The tumour suppressor hSNF5/INI1 controls the differentiation potential of malignant rhabdoid cells

✍ Scribed by Patricia Albanese; Marie-France Belin; Olivier Delattre

Book ID: 116428998
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 573 KB
Volume: 42
Category: Article
ISSN: 0959-8049
DOI: 10.1016/j.ejca.2006.03.028

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## Abstract The __hSNF5/INI1__ gene, which encodes a subunit of the SWI/SNF family of chromatin‐remodeling complexes and is located at 22q11.2, has been reported as a tumor suppressor gene inactivated in malignant rhabdoid tumors (MRTs). We analyzed this gene in varieties of pediatric solid tumors

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