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The tryptophan depletion test: impact on sleep in primary insomnia — a pilot study

✍ Scribed by Dieter Riemann; Bernd Feige; Magdolna Hornyak; Stephanie Koch; Fritz Hohagen; Ulrich Voderholzer

Book ID
117333985
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
121 KB
Volume
109
Category
Article
ISSN
0165-1781

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We studied 12 healthy subjects, six males and six females, using the technique of tryptophan depletion in a doubleblind placebo controlled crossover design. Subjects rated their subjective mood and also underwent a mood induction procedure. The tryptophan free mixture signi®cantly lowered plasma tot