## Neubauer et al. (1) report on the spin-lattice relaxation times (T,) of high-energy phosphates in the human myocardium at 1.5 T. Their values of 6.1 ? 0.5 (SD) s for PCr and 5.4 t 0.5 s to 5.8 +-1 s for the ATP phosphates differ
The true T1 values of myocardial high-energy phosphates?
β Scribed by Stefan Neubauer; Michael Horn; Wolfgang R. Bauer; George Ertl; Thomas Krahe; Rolf Schindler; Axel Haase
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 218 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0740-3194
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The measurement of myocardial high-energy phosphates (HEP) has become essential in the evaluation of current methods of myocardial protection both in the experimental and clinical setting. Assays for high-energy phosphates have required as much as 50 mg of myocardial tissue which prevents repeated b
## Abstract Whether changes of cardiac highβenergy phosphate concen trations occur over the cardiac cycle remains controversial. The hypothesis was that such cyclical changes are accentu ated during acute or chronic myocardial stress. Isolated rat hearts were perfused under four conditions: (1) con