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The Triple Helix: Gene, Organism and Environment

✍ Scribed by Nathan, David G.; Varmus, Harold E.


Book ID
109829364
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
128 KB
Volume
6
Category
Article
ISSN
1078-8956

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## Abstract Collagen is an abundant, triple‐helical protein comprising three strands of the repeating sequence: Xaa–Yaa–Gly. (2S)‐Proline and (2S,4R)‐4‐hydroxyproline (Hyp) are common in the primary structure of collagen. Here, we use nonnatural proline derivatives to reveal determinants of collage