๐”– Bobbio Scriptorium
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The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomes

โœ Scribed by L. Carrasco; M. Barbacid; D. Vazquez

Book ID
115745458
Publisher
Elsevier Science
Year
1973
Weight
520 KB
Volume
312
Category
Article
ISSN
0005-2787

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The effect of spermine on the binding of AcPhe-tRNA to poly(U)-programmed ribosomes (step 1) and on the puromycin reaction (step 2) has been studied in a cell-free system, derived from E. coli. In the absence of ribosomal wash (FWR fraction) and at suboptimal concentration of Mg++ (6 mM), spermine s