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The transplacental passage of prednisone and prednisolone in pregnancy near term

✍ Scribed by Inese Z. Beitins; Francis Bayard; Isadore G. Ances; Avinoam Kowarski; Claude J. Migeon

Book ID: 118537215
Publisher: Elsevier Science
Year: 1972
Tongue: English
Weight: 663 KB
Volume: 81
Category: Article
ISSN: 1097-6833
DOI: 10.1016/s0022-3476(72)80547-x

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The protein binding characteristics of prednisone and prednisolone were determined in human and rabbit plasma and in a 4.7 per cent human serum albumin (HSA) solution. The influence of plednisolone on prednisone binding in human plasma was also examined. Prednisolone exhibited nonlinear binding and