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The Transmembrane Domains of the EBV-Encoded Latent Membrane Protein 1 (LMP1) Variant CAO Regulate Enhanced Signalling Activity

✍ Scribed by Sarah M.S. Blake; Aristides G. Eliopoulos; Christopher W. Dawson; Lawrence S. Young


Book ID
112273490
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
354 KB
Volume
282
Category
Article
ISSN
0042-6822

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Two genes encoding the latent membrane protein 1 (LMP1) of the Epstein-Barr virus (EBV) were isolated from a single case of Hodgkin's disease (HD) and were tested for their biological activities. The LMP1 gene from the Reed-Sternberg cells contained point mutations relative to the prototype LMP1 gen