Molecular modeling of c-erbB2 receptor d
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Norbert Garnier; Daniel Genest; Jean Pierre Duneau; Monique Genest
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Article
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1997
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Wiley (John Wiley & Sons)
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English
⚖ 210 KB
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Dimerization models of c-erbB2 transmembrane domains (Leu651-Ile675) are studied by molecular mechanics and molecular dynamics simulations. Both wild and Glu mutated transmembrane helices exhibit the same relative orientation for favorable associations and dimerize preferentially in left-handed coil