The transition of pemphigus vulgaris into pemphigus foliaceus: a reflection of changing desmoglein 1 and 3 autoantibody levels in pemphigus vulgaris
β Scribed by K.E. Harman; M.J. Gratian; P.J. Shirlaw; B.S. Bhogal; S.J. Challacombe; M.M. Black
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 146 KB
- Volume
- 146
- Category
- Article
- ISSN
- 0007-0963
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π SIMILAR VOLUMES
## Background: Pemphigus vulgaris (pv) autoantibodies (pv-igg) have been found in 40-70% of sera of first-degree relatives of pemphigus patients. ## Objectives: To determine the possible role of pv-igg subclasses in the pathogenesis of the disease. ## Patients and methods: Study groups comprise
## Background: Pemphigus vulgaris (pv) is characterized by pathogenic autoantibodies to desmoglein (dsg) 3, but additional antibodies to dsg1, the pemphigus foliaceus antigen, are detectable in some cases. ## Objectives: To investigate the clinical significance of the presence of both dsg 1 and 3