✦ LIBER ✦
The transfer of radioactivity of HSA-containing samples of 125I insulin preparations during their storage
✍ Scribed by J. Kopoldová
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- French
- Weight
- 325 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
In ^125^I insulin preparations, preserved in the form of lyophilized solutions with human serum albumin, the transfer of radioactivity from the insulin molecules to the higher molecular weight fractions was observed. After one month storage this transfer corresponded to 7 % of the total radioactivity and it increased proportionally to the length of the storage of iodinated preparations under simultaneous decrease of their biological activity. The results obtained with stored ^125^I insulin preparations and these preparations irradiated with external gamma‐source were compared and discussed.