The transcription factor Sox11 is a prognostic factor for improved recurrence-free survival in epithelial ovarian cancer
✍ Scribed by Donal J. Brennan; Sara Ek; Emma Doyle; Thomas Drew; Michael Foley; Grainne Flannelly; Darran P. O’Connor; William M. Gallagher; Sami Kilpinen; Olli-Pekka Kallioniemi; Karin Jirstrom; Colm O’Herlihy; Carl A.K. Borrebaeck
- Book ID
- 116429972
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 540 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0959-8049
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High levels of plasminogen activator inhibitor-1 (PAI-1) in tissue extracts have been associated with poor prognosis in many epithelial cancers. Ovarian cancers contain a higher concentration of PAI-1 than benign ovarian tumors or normal ovaries. Reports, however, on the prognostic value of PAI-1 co
## Background: The aim of this study was to determine the prognostic significance of preoperative serum inhibin and activin levels in postmenopausal women with epithelial ovarian carcinoma (eoc) by correlating serum levels with disease parameters, including tumor stage and grade and patient age. #