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The toxic effect of pyrrolizidine alkaloid clivorine on the human embryonic kidney 293 cells and its primary mechanism

✍ Scribed by Li-Li Ji; Ying Chen; Zheng-Tao Wang

Book ID
113607894
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
450 KB
Volume
60
Category
Article
ISSN
0940-2993

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Fumonisins are mycotoxins produced by Fusarium verticillioides. The toxic effects of fumonisin B 1 (FB 1 ) at the cellular level consist of a mixture of both necrosis and apoptosis. We studied the effect of FB 1 in human lung fibroblasts (NHLF) and human kidney epithelial cells (RPTEC) in primary cu