We have previously shown that amiloride, an inhibitor of several cell membrane sodium exchangers and channels including Na/H exchange and Na/Ca exchange, inhibits receptor-operated contraction of bovine airway smooth muscle. However, the precise mechanism of action of amiloride is unknown. To evalua
The toxic effect of an AChE-inhibitor on the cholinergic nervous system in airway smooth muscle
✍ Scribed by Pål Aas
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 375 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0300-483X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
SUMMARY: We studied the role of sodium transport and calcium channels in protein kinase \(C\) mediated signaltransduction pathways in bovine airway smooth muscle. 4- \(\beta\) phorbol 12,13 dibutyrate (PDB), an activator of protein kinase \(C\), caused dose-related slowly developing contraction in b
Experiments were made on isolated tissues from guinea-pig to test the hypothesis that the distomers of rac-Pzadrenoceptor agonists induce airway hyperreactivity. Tracheal strip preparations were contracted with carbachol. Both racand (RR)-formoterol (2 and 1 kmol/l, respectively) produced an immedia