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The Total Synthesis of the Annonaceous Acetogenin, Muricatetrocin C

✍ Scribed by Darren J. Dixon; Steven V. Ley; Dominic J. Reynolds

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
375 KB
Volume
8
Category
Article
ISSN
0947-6539

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✦ Synopsis

The total synthesis of the potential antitumour agent muricatetrocin C has provided an ideal stage for the exploitation and development of new chemistry. A convergent synthetic strategy has been realised incorporating three distinct pieces of methodology, these include a highly diastereoselective hetero-Diels Β± Alder reaction to construct the butenolide terminus, an oxygen to carbon rearrangement to install the trans-2,5-disubstituted tetrahydrofuran ring and a spatial desymmetrisation process to afford the anti-diol unit.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: The Total Synthesis
ChemInform Abstract: The Total Synthesis of the Annonaceous Acetogenin, Muricatetrocin C.
✍ Darren J. Dixon; Steven V. Ley; Dominic J. Reynolds πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons βš– 25 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

ChemInform Abstract: The Total Synthesis
ChemInform Abstract: The Total Synthesis of the Annonaceous Acetogenin, Muricatetrocin C.
✍ Darren J. Dixon; Steven V. Ley; Dominic J. Reynolds πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 24 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v