The Total Synthesis of Cedrol and Cedrene
โ Scribed by Stork, Gilbert; Clarke, Frank H.
- Book ID
- 120277832
- Publisher
- American Chemical Society
- Year
- 1955
- Tongue
- English
- Weight
- 253 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
The tricyclic sesquiterpenoids cedrol (I) and cedrene (II) have long been focal points for chemical investigation. l-5 In continuation of previous research in this Laboratory, 5a we projected a synthesis involving as a key step the direct conversion of the cation III (or equivalent) to cedrone IV. O
## Abstract A concise entry into the bicyclic cyclopropyl ketone derivatives **5** and **6** by way of a goldโcatalyzed OhloffโRautenstrauchโtype enyne cycloisomerization is described. The required substrates were prepared by an asymmetric addition of the branched allylzinc reagent **21** to the al