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The total synthesis of (+)-16-hydroxydihydrocleav-amine and the partial synthesis of demethoxy-carbonyldeoxyvinblastine

✍ Scribed by J. Harley-Mason; Atta-Ur-Rahman


Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
706 KB
Volume
36
Category
Article
ISSN
0040-4020

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We wish to communicate the first synthesis of l-methyl-16-demethoxycarbonyl-20-desetbylidenevobaeine(1) having the carbon skeleton of the P-acylindole alkaloids which are repreeented by vobad.ne(II)(l). I : B=CHJ, Br=H, &=H,H I1 : R=H, B1=COnCH3, B2=&HC& Catalytic hydrogenation of N-bensylidenetrypt