Drug efflux transporters in rheumatoid a
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Samantha L. Hider; Patrick Hoggard; Saye Khoo; David Back; Ian N. Bruce
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Article
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2005
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John Wiley and Sons
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English
β 125 KB
π 1 views
We read with interest the article by Kremer (1) reviewing the mechanisms of action of methotrexate (MTX) and potential mechanisms of MTX resistance. One facet that Kremer highlighted is the role of drug efflux transporters in mediating resistance to MTX. Although he highlights the role of multidrug