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The tissue distribution in BALB/c mice of C-14-labeled JM216, an orally active platinum antitumour compound

โœ Scribed by P. I. Bates; H. L. Sharma; B. A. Murrer; C. A. McAuliffe


Book ID
105994128
Publisher
Springer
Year
1996
Tongue
English
Weight
133 KB
Volume
39
Category
Article
ISSN
0344-5704

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Since the reactivity of carboplatin depends on the rate of removal of the 1,1-cyclobutanedicarboxylate ligand, the time course of this dissociation has been determined in various tissue and body fluids using 14C-labelled carboplatin (cis-diammine[1,1-cyclobutane-1-14C-dicarboxylate]platinum II). Mic